Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.53 |
| ▸ | PPARA | Q07869 | 9/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL82055 | 1.00 | PPARG (0.53) | PPARGPPARAADORA3ELANENPSR1 | |
| SCHEMBL4550641 | 0.90 | PPARA (0.54) | PPARGPPARAADORA3 | |
| SCHEMBL3966243 | 0.88 | PPARA (0.52) | PPARGPPARAADORA3 | |
| SCHEMBL11548438 | 0.88 | ADORA3 (0.48) | PPARGPPARAADORA3ELANEL3MBTL1 | |
| SCHEMBL29129794 | 0.87 | PPARG (0.51) | PPARGPPARA | |
| SCHEMBL5531801 | 0.86 | ADORA3 (0.47) | PPARGPPARAADORA3ELANEMEN1 | |
| SCHEMBL9417313 | 0.86 | PPARA (0.53) | PPARGPPARAADORA3ELANEMEN1 | |
| SCHEMBL1960387 | 0.85 | PPARG (0.62) | PPARGPPARAADORA3ELANENPSR1 | |
| SCHEMBL4852302 | 0.85 | PPARA (0.49) | PPARGPPARAADORA3ELANEMEN1 | |
| SCHEMBL2560059 | 0.85 | L3MBTL1 (0.50) | PPARGPPARAADORA3ELANENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491167-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY, LIMITED (JP) | 1996-02-13 | — | — | US | disclosed |