Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORA | P35398 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | RORB | Q92753 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CTSV | O60911 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11245349 | 0.90 | GSK3A (0.36) | RORARORCRORBGSK3AGSK3B | |
| SCHEMBL11235510 | 0.89 | RORA (0.36) | RORARORCRORBGSK3AGSK3B | |
| SCHEMBL11236537 | 0.87 | GSK3A (0.39) | GSK3AGSK3BALDH1A1KDM4ELMNA | |
| SCHEMBL11063409 | 0.83 | RORA (0.38) | RORARORCRORBPLA2G2AALDH1A1 | |
| SCHEMBL11253082 | 0.83 | SMN1; SMN2 (0.40) | GSK3AGSK3BALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11067919 | 0.78 | RORA (0.43) | RORARORCRORBPLA2G2AALDH1A1 | |
| SCHEMBL11249686 | 0.77 | TRPV1 (0.34) | ALDH1A1HPGDCNR2KMT2A | |
| SCHEMBL11239963 | 0.77 | CNR2 (0.36) | ALDH1A1LMNAHPGDCNR2MEN1 | |
| SCHEMBL11239203 | 0.77 | GSK3A (0.42) | GSK3AGSK3BNPY5RALDH1A1KDM4E | |
| SCHEMBL11242383 | 0.76 | GSK3A (0.38) | GSK3AGSK3BNPY5RALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337340-A | FROM DIPHENYLAMINES AND BENZOYL OR 3-INDOLYLCARBONYL PYRIDINE- OR PYRAZINECARBOXYLIC ACIDS | STERLING DRUG INC. (US) | 1982-06-29 | — | — | US | disclosed |
| US-4243250-A | FUROPYRIDINONES OR FUROPYRAZINONES AS COLOR FORMERS | STERLING DRUG INC. (US) | 1981-01-06 | — | — | US | disclosed |
| US-4211872-A | COLOR FORMERS | FREEDOM CHEMICAL COMPANY | 1980-07-08 | — | — | US | disclosed |