Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 3/20 | 0.32 |
| ▸ | THRB | P10828 | 3/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | CDC25A | P30304 | 1/20 | 0.32 |
| ▸ | CDC25B | P30305 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | LPL | P06858 | 3/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11239963 | 0.91 | CNR2 (0.36) | TRPV1ALDH1A1CYP1A2CYP3A4HPGD | |
| SCHEMBL11237226 | 0.87 | TRPV1 (0.36) | TRPV1ALDH1A1CYP1A2CYP3A4HPGD | |
| SCHEMBL11244452 | 0.87 | TRPV1 (0.36) | TRPV1ALDH1A1CYP1A2CYP3A4HPGD | |
| SCHEMBL11241310 | 0.81 | CNR2 (0.32) | TRPV1ALDH1A1CYP1A2CYP3A4HPGD | |
| SCHEMBL1882657 | 0.78 | KMT2A (0.42) | ALDH1A1CYP1A2CYP3A4HPGDCYP2C19 | |
| SCHEMBL11373082 | 0.78 | ALDH1A1 (0.51) | ALDH1A1CYP1A2CYP3A4HPGDCYP2C19 | |
| SCHEMBL11250433 | 0.77 | RORA (0.36) | ALDH1A1HPGDKMT2ACNR2 | |
| SCHEMBL11237151 | 0.72 | LMNA (0.32) | TRPV1CYP2C19CNR2FAAH | |
| SCHEMBL10715437 | 0.70 | ALDH1A1 (0.50) | ALDH1A1CYP1A2CYP3A4HPGDCYP2C19 | |
| SCHEMBL11243411 | 0.70 | TRPV1 (0.37) | TRPV1ALDH1A1CYP1A2CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337340-A | FROM DIPHENYLAMINES AND BENZOYL OR 3-INDOLYLCARBONYL PYRIDINE- OR PYRAZINECARBOXYLIC ACIDS | STERLING DRUG INC. (US) | 1982-06-29 | — | — | US | disclosed |
| US-4243250-A | FUROPYRIDINONES OR FUROPYRAZINONES AS COLOR FORMERS | STERLING DRUG INC. (US) | 1981-01-06 | — | — | US | disclosed |
| US-4211872-A | COLOR FORMERS | FREEDOM CHEMICAL COMPANY | 1980-07-08 | — | — | US | disclosed |