Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 3/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11232126 | 0.95 | KDM4E (0.37) | GSK3AGSK3BKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL11237223 | 0.94 | MAPT (0.35) | GSK3AGSK3BKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL11245671 | 0.93 | ALDH1A1 (0.38) | GSK3AGSK3BKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL11247969 | 0.93 | SMN1; SMN2 (0.39) | GSK3AGSK3BKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL29044637 | 0.89 | GSK3A (0.40) | GSK3AGSK3BKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL11235510 | 0.88 | RORA (0.36) | GSK3AGSK3BMEN1KMT2ANPY5R | |
| SCHEMBL11236537 | 0.87 | GSK3A (0.39) | GSK3AGSK3BKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL3877954 | 0.85 | ALDH1A1 (0.38) | KDM4ESMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL11239203 | 0.85 | GSK3A (0.42) | GSK3AGSK3BKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL11239907 | 0.82 | GSK3A (0.43) | GSK3AGSK3BKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4211872-A | COLOR FORMERS | FREEDOM CHEMICAL COMPANY | 1980-07-08 | — | — | US | claimed |
| US-4337340-A | FROM DIPHENYLAMINES AND BENZOYL OR 3-INDOLYLCARBONYL PYRIDINE- OR PYRAZINECARBOXYLIC ACIDS | STERLING DRUG INC. (US) | 1982-06-29 | — | — | US | disclosed |
| US-4243250-A | FUROPYRIDINONES OR FUROPYRAZINONES AS COLOR FORMERS | STERLING DRUG INC. (US) | 1981-01-06 | — | — | US | disclosed |
| US-4211872-A | COLOR FORMERS | FREEDOM CHEMICAL COMPANY | 1980-07-08 | — | — | US | disclosed |