Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | ICMT | O60725 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.36 |
| ▸ | CHRNG | P07510 | 1/20 | 0.36 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11239617 | 0.94 | SLC6A4 (0.37) | SMN1; SMN2MAOBICMTMAOACA12 | |
| SCHEMBL1593292 | 0.90 | SMN1; SMN2 (0.36) | SMN1; SMN2MAOBICMTMAOAPOLB | |
| SCHEMBL11237020 | 0.89 | RYR2 (0.36) | SMN1; SMN2MAOBICMTMAOAPOLB | |
| SCHEMBL12134317 | 0.86 | SMN1; SMN2 (0.40) | SMN1; SMN2MAOBMAOAPOLBNPC1 | |
| SCHEMBL11246464 | 0.86 | GRIN1 (0.40) | SMN1; SMN2MAOBICMTMAOACA12 | |
| SCHEMBL10848899 | 0.83 | MAOB (0.41) | SMN1; SMN2MAOBICMTMAOAPOLB | |
| SCHEMBL11239210 | 0.83 | RYR2 (0.35) | SMN1; SMN2MAOBICMTMAOAALDH1A1 | |
| SCHEMBL11246261 | 0.81 | TSHR (0.43) | NPC1RAB9ACA12CA1CA2 | |
| SCHEMBL11242731 | 0.81 | L3MBTL1 (0.34) | MAOBICMTMAOAALDH1A1CHRNA1 | |
| SCHEMBL2082060 | 0.81 | CA12 (0.41) | SMN1; SMN2MAOBMAOAPOLBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |