Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11254398 | 1.00 | MAPT (0.47) | MAPTKDM4ENPSR1LMNANPC1 | |
| SCHEMBL11250703 | 1.00 | MAPT (0.47) | MAPTKDM4ENPSR1LMNANPC1 | |
| SCHEMBL7130236 | 0.81 | CYP2C19 (0.60) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22758099 | 0.81 | CYP2C19 (0.60) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10332381 | 0.80 | CA1 (0.47) | MAPTKDM4ELMNAPKMALDH1A1 | |
| SCHEMBL11520468 | 0.79 | NPC1 (0.50) | MAPTLMNANPC1RAB9AMEN1 | |
| Methoxymethane SCHEMBL22492722 | 0.72 | PARP10 (0.54) | MAPTKDM4ENPSR1LMNAKMT2A | |
| SCHEMBL11520656 | 0.72 | CES2 (0.46) | MAPTKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL8588467 | 0.71 | CYP2C19 (0.52) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11263999 | 0.71 | ADORA3 (0.53) | MAPTKDM4ENPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327213-A | ANTIULCER AGENTS | ACF Chemiefarma VA (NL) | 1982-04-27 | — | — | US | disclosed |