Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 8/20 | 0.45 |
| ▸ | RAB9A | P51151 | 8/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.45 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22758099 | 1.00 | CYP2C19 (0.60) | CYP2C19GAATSHRNPC1RAB9A | |
| SCHEMBL8588467 | 0.89 | CYP2C19 (0.52) | CYP2C19GAATSHRNPC1RAB9A | |
| SCHEMBL3958996 | 0.84 | TSHR (0.48) | CYP2C19GAATSHRNPC1RAB9A | |
| SCHEMBL8007984 | 0.84 | TSHR (0.48) | CYP2C19GAATSHRNPC1RAB9A | |
| SCHEMBL3689392 | 0.84 | TSHR (0.48) | CYP2C19GAATSHRNPC1RAB9A | |
| SCHEMBL2045474 | 0.83 | TSHR (0.44) | CYP2C19GAATSHRNPC1RAB9A | |
| SCHEMBL2045476 | 0.83 | TSHR (0.44) | CYP2C19GAATSHRNPC1RAB9A | |
| SCHEMBL25314654 | 0.83 | CYP2C19 (0.58) | CYP2C19GAATSHRNPC1RAB9A | |
| SCHEMBL11521468 | 0.83 | CYP2C19 (0.58) | CYP2C19GAATSHRNPC1RAB9A | |
| SCHEMBL10332381 | 0.83 | CA1 (0.47) | CYP2C19GAATSHRMAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4264597-A | FUNGICIDES | FUJISAWA PHARMACEUTICAL CO., LTD., NO. 3, 4-CHOME, DOSHOMACHI, HIGASHI-KU, OSAKA, JAPAN | 1981-04-28 | — | — | US | claimed |
| CN-100383116-C | Methoximinophenylacetic acid amides | BAYER AG (DE) | 2008-04-23 | — | — | CN | disclosed |
| CN-100383116-C | Methoximinophenylacetic acid amides | BAYER AG (DE) | 2008-04-23 | — | — | CN | disclosed |
| EP-1105372-B1 | METHOXIMINOPHENYLACETIC ACID AMIDES | BAYER CROPSCIENCE AG (DE) | 2003-06-11 | — | — | EP | disclosed |
| US-6403600-B1 | FUNGICIDES. | BAYER AKTIENGESELLSCHAFT (DE) | 2002-06-11 | — | — | US | disclosed |
| US-6403600-B1 | FUNGICIDES. | BAYER AKTIENGESELLSCHAFT (DE) | 2002-06-11 | — | — | US | disclosed |
| US-6403600-B1 | FUNGICIDES. | BAYER AKTIENGESELLSCHAFT (DE) | 2002-06-11 | — | — | US | disclosed |
| CN-1316990-A | Methoximinophenylacetic acid amides | BAYER AG (DE) | 2001-10-10 | — | — | CN | disclosed |
| CN-1316990-A | Methoximinophenylacetic acid amides | BAYER AG (DE) | 2001-10-10 | — | — | CN | disclosed |
| EP-1105372-A1 | METHOXIMINOPHENYLACETIC ACID AMIDES | BAYER AG (DE) | 2001-06-13 | — | — | EP | disclosed |
| EP-0271829-A2 | Delta-hydroxy-beta-lysine derivatives and their production | Takeda Chemical Industries, Ltd. (JP) | 1988-06-22 | — | — | EP | disclosed |
| US-4725591-A | USED WITH AMINO ACID DERIVATIVE ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-02-16 | — | — | US | disclosed |
| EP-0253337-A2 | Tricyclic cepham compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1988-01-20 | — | — | EP | disclosed |
| EP-0249909-A1 | Tricyclic penam compounds, their production and their use | Takeda Chemical Industries, Ltd. (JP) | 1987-12-23 | — | — | EP | disclosed |
| EP-0250096-A1 | Isoxazolone derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-12-23 | — | — | EP | disclosed |
| EP-0219923-A1 | Antibiotic derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-04-29 | — | — | EP | disclosed |
| EP-0191989-A1 | Antibiotic isoxazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1986-08-27 | — | — | EP | disclosed |
| US-4342760-A | ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1982-08-03 | — | — | US | disclosed |
| US-4264597-A | FUNGICIDES | FUJISAWA PHARMACEUTICAL CO., LTD., NO. 3, 4-CHOME, DOSHOMACHI, HIGASHI-KU, OSAKA, JAPAN | 1981-04-28 | — | — | US | disclosed |
| US-4144391-A | REPLACING AN ACETOXY GROUP BY A SULFUR NUCLEOPHILE | ELI LILLY AND COMPANY (US) | 1979-03-13 | — | — | US | disclosed |