Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL445252 | 0.93 | ALDH1A1 (0.53) | ALDH1A1TSHRCA1CA2CA12 | |
| SCHEMBL15013120 | 0.85 | DNM1 (0.53) | ALDH1A1CA1CA2CA12CA9 | |
| SCHEMBL1922659 | 0.85 | ALDH1A1 (0.54) | ALDH1A1CA1CA2CA12CA9 | |
| SCHEMBL10486780 | 0.82 | CA1 (0.62) | ALDH1A1CA1CA2CA12CA9 | |
| SCHEMBL6009330 | 0.82 | ALDH1A1 (0.49) | ALDH1A1CA1CA2CA12CA9 | |
| SCHEMBL9685017 | 0.80 | ALDH1A1 (0.47) | ALDH1A1CA1CA2CA12CA9 | |
| SCHEMBL16450791 | 0.76 | CA1 (0.45) | ALDH1A1TSHRCA1CA2CA12 | |
| SCHEMBL6357771 | 0.76 | ALDH1A1 (0.47) | ALDH1A1TSHRCA1CA2CA12 | |
| SCHEMBL11409290 | 0.76 | ALDH1A1 (0.46) | ALDH1A1TSHRCA1CA2CA12 | |
| SCHEMBL885320 | 0.74 | KDM4E (0.65) | ALDH1A1TSHRKDM4EDNM1PAOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4310632-A | POLYMERIZATION CATALYST OF A DIALKYLAMINO GUANIDINE, UREA OR THIOU | BASF AKTIENGESELLSCHAFT (DE) | 1982-01-12 | — | — | US | disclosed |