SCHEMBL6009330

SCHEMBL6009330

CNC(=S)NCCCN(C)C

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.49
SMN1; SMN2 Q16637 1/20 0.45
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA12 O43570 1/20 0.42
CA9 Q16790 1/20 0.42
DNM1 Q05193 1/20 0.42
QPCT Q16769 1/20 0.41
PKM P14618 1/20 0.41
POLB P06746 2/20 0.40
RECQL P46063 1/20 0.40
HRH2 P25021 2/20 0.39
HRH4 Q9H3N8 1/20 0.39
HRH3 Q9Y5N1 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
KDM4E B2RXH2 2/20 0.39
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL445252 0.89 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2CA1CA2CA12
SCHEMBL10941126 0.86 CA1 (0.56) ALDH1A1CA1CA2CA12CA9
SCHEMBL11250825 0.82 ALDH1A1 (0.47) ALDH1A1SMN1; SMN2CA1CA2CA12
SCHEMBL9685017 0.81 ALDH1A1 (0.47) ALDH1A1SMN1; SMN2CA1CA2CA12
SCHEMBL1922659 0.81 ALDH1A1 (0.54) ALDH1A1SMN1; SMN2CA1CA2CA12
SCHEMBL15013120 0.81 DNM1 (0.53) ALDH1A1SMN1; SMN2CA1CA2CA12
SCHEMBL9948686 0.79
SCHEMBL17758508 0.79 NPC1 (0.54) ALDH1A1QPCTHRH2HRH4HRH3
SCHEMBL6357771 0.77 ALDH1A1 (0.47) ALDH1A1SMN1; SMN2CA1CA2CA12
SCHEMBL16450791 0.77 CA1 (0.45) ALDH1A1SMN1; SMN2CA1CA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7022721-B1 Method and composition for rejuvenating cells, tissues, organs, hair and nails ULRICH PETER C 2006-04-04 US disclosed
EP-1368029-A4 METHOD AND COMPOSITION FOR REJUVINATING CELLS, TISSUES, ORGANS, HAIR AND NAILS FARRINGTON PHARMACEUTICALS LLC (US) 2006-02-15 EP disclosed
US-20050245512-A1 Method and composition for rejuvinating cells, tissues organs, hair and nails ULRICH PETER C 2005-11-03 US disclosed
US-6777557-B2 Method and composition for rejuvenating cells, tissues organs, hair and nails FARRINGTON PHARMACEUTICALS, LLC 2004-08-17 US disclosed
EP-1368029-A2 METHOD AND COMPOSITION FOR REJUVINATING CELLS, TISSUES, ORGANS, HAIR AND NAILS Farrington Pharmaceuticals, LLC (US) 2003-12-10 EP disclosed
US-20020188015-A1 Method and composition for rejuvinating cells, tissues organs, hair and nails FARRINGTON PHARMACEUTICALS, LLC 2002-12-12 US disclosed
WO-2002062301-A2 METHOD AND COMPOSITION FOR REJUVINATING CELLS, TISSUES, ORGANS, HAIR AND NAILS FARRINGTON PHARMACEUTICALS, LLC (US) 2002-08-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020188015-A1 Method and composition for rejuvinating cells, tissues organs, hair and nails TERT, TELO2, HKDC1 ALDH1A1 3396/4885SMN1; SMN2 2608/4885CA1 4196/4885
US-20050245512-A1 Method and composition for rejuvinating cells, tissues organs, hair and nails TERT, TELO2, HKDC1 ALDH1A1 3396/4885SMN1; SMN2 2608/4885CA1 4196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.