Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL512776 | 0.80 | GRIN2D (0.39) | LMNAGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL11552604 | 0.76 | TSHR (0.36) | MEN1KMT2ACYP2C9 | |
| SCHEMBL25368706 | 0.76 | GRIN2D (0.44) | LMNAGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL435412 | 0.76 | GRIN2D (0.44) | LMNAGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL11248334 | 0.73 | GAA (0.43) | GAAMEN1KMT2AALDH1A1POLB | |
| SCHEMBL8673707 | 0.70 | LMNA (0.36) | LMNAGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL8675369 | 0.70 | LMNA (0.36) | LMNAGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL11244880 | 0.69 | LMNA (0.35) | LMNAGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL8678113 | 0.67 | LMNA (0.38) | LMNAGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL9570551 | 0.65 | SIGMAR1 (0.43) | MEN1KMT2AALDH1A1CYP2C9SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337341-A | 4a-Aryl-octahydro-1H-2-pyrindines | ELI LILLY AND COMPANY (US) | 1982-06-29 | — | — | US | disclosed |