Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11256045 | 0.86 | ALDH1A1 (0.38) | GAAALDH1A1SLC6A4MEN1KMT2A | |
| SCHEMBL11188355 | 0.79 | GAA (0.47) | GAAOPRM1ALDH1A1OPRD1OPRK1 | |
| SCHEMBL9316420 | 0.73 | CYP3A4 (0.42) | GAAOPRM1ALDH1A1OPRD1OPRK1 | |
| SCHEMBL11250871 | 0.73 | LMNA (0.34) | GAAALDH1A1SIGMAR1MEN1CYP2C9 | |
| SCHEMBL11257471 | 0.71 | GAA (0.42) | GAAOPRM1ALDH1A1OPRD1OPRK1 | |
| SCHEMBL11552604 | 0.71 | TSHR (0.36) | MEN1CYP2C9KMT2AHTT | |
| SCHEMBL11188344 | 0.70 | GAA (0.43) | GAAOPRM1ALDH1A1OPRD1OPRK1 | |
| SCHEMBL9181522 | 0.69 | GAA (0.62) | GAAOPRM1ALDH1A1OPRD1OPRK1 | |
| SCHEMBL11541268 | 0.68 | OPRM1 (0.43) | GAAOPRM1ALDH1A1SMN1; SMN2CYP2C19 | |
| SCHEMBL11250243 | 0.67 | OPRM1 (0.42) | GAAOPRM1OPRD1OPRK1SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337341-A | 4a-Aryl-octahydro-1H-2-pyrindines | ELI LILLY AND COMPANY (US) | 1982-06-29 | — | — | US | disclosed |