Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 3/20 | 0.40 |
| ▸ | PDE1A | P54750 | 1/20 | 0.40 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.40 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 6/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11241379 | 0.84 | LMNA (0.36) | PDE5AAOC3POLBALDH1A1MAPT | |
| SCHEMBL11239873 | 0.77 | AOC3 (0.47) | PDE5APDE1APDE1BPDE1CAOC3 | |
| SCHEMBL11249355 | 0.77 | AOC3 (0.46) | PDE5APDE1APDE1BPDE1CAOC3 | |
| SCHEMBL10980964 | 0.74 | AOC3 (0.39) | ADRB2ADRB1ADRB3PDE5APDE1A | |
| Hydrochloric Acid SCHEMBL11239003 | 0.74 | AOC3 (0.43) | PDE5APDE1APDE1BPDE1CAOC3 | |
| SCHEMBL11251596 | 0.74 | PDE5A (0.46) | PDE5APDE1APDE1BPDE1CAOC3 | |
| SCHEMBL10675326 | 0.71 | AOC3 (0.46) | PDE5APDE1APDE1BPDE1CAOC3 | |
| SCHEMBL11251923 | 0.71 | GAA (0.53) | POLBALDH1A1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL11241637 | 0.71 | AOC3 (0.41) | PDE5APDE1APDE1BPDE1CAOC3 | |
| SCHEMBL11239646 | 0.71 | AOC3 (0.41) | PDE5APDE1APDE1BPDE1CAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362736-A | ANTISECRETORY AGENTS, GASTRIC JUICE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1982-12-07 | — | — | US | disclosed |