Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | SLC22A3 | O75751 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA6 | P23280 | 2/20 | 0.36 |
| ▸ | HRH2 | P25021 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.36 |
| ▸ | POU5F1 | Q01860 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | SLC47A2 | Q86VL8 | 2/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.36 |
| ▸ | SLC47A1 | Q96FL8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11251663 | 0.84 | ADRB2 (0.41) | LMNACA12CA1CA2CA9 | |
| SCHEMBL11388323 | 0.82 | ALDH1A1 (0.40) | LMNASLC22A2CA12SLC22A3CA1 | |
| SCHEMBL11239700 | 0.82 | AOC3 (0.42) | LMNAPDE5AALDH1A1AOC3MEN1 | |
| SCHEMBL10585196 | 0.78 | SLC22A2 (0.41) | LMNASLC22A2CA12SLC22A3CA1 | |
| SCHEMBL11241210 | 0.78 | SMN1; SMN2 (0.39) | LMNASLC22A2CA12SLC22A3CA1 | |
| SCHEMBL9817424 | 0.77 | HRH2 (0.40) | LMNASLC22A2CA12SLC22A3CA1 | |
| SCHEMBL10587291 | 0.76 | HRH2 (0.39) | LMNASLC22A2CA12SLC22A3CA1 | |
| SCHEMBL10678909 | 0.76 | ALDH1A1 (0.39) | LMNASLC22A2CA12SLC22A3CA1 | |
| SCHEMBL10678904 | 0.76 | ALDH1A1 (0.39) | LMNASLC22A2CA12SLC22A3CA1 | |
| SCHEMBL11394438 | 0.76 | KMT2A (0.47) | LMNATSHRALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362736-A | ANTISECRETORY AGENTS, GASTRIC JUICE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1982-12-07 | — | — | US | disclosed |