Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | AKT2 | P31751 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11252500 | 0.86 | AKR1B1 (0.53) | ALPGAKR1B1ALDH1A1GAAPOLB | |
| SCHEMBL5926012 | 0.83 | CHRM4 (0.43) | HTR6ALDH1A1GAAPOLBTGFBR1 | |
| SCHEMBL12545009 | 0.78 | HTR6 (0.42) | ALPGHTR6ALDH1A1GAAPOLB | |
| SCHEMBL11167850 | 0.77 | ALDH1A1 (0.45) | ALDH1A1GAAPOLBLMNAKDM4E | |
| SCHEMBL21500652 | 0.75 | F2RL1 (0.56) | HTR6ALDH1A1TGFBR1AKT1AKT2 | |
| SCHEMBL11164413 | 0.75 | HTR6 (0.36) | ALPGHTR6AKR1B1ALDH1A1GAA | |
| SCHEMBL18774145 | 0.74 | GAA (0.53) | ALDH1A1GAAPOLBLMNAKDM4E | |
| SCHEMBL11171275 | 0.74 | ALPG (0.46) | ALPGAKR1B1ALDH1A1GAAPOLB | |
| SCHEMBL11168383 | 0.74 | KDM4E (0.43) | ALPGHTR6AKR1B1ALDH1A1GAA | |
| SCHEMBL11231988 | 0.71 | ALDH1A1 (0.58) | ALPGHTR6AKR1B1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107531696-B | Pyridopyrimidinones as NMDA receptor modulators and their use | 豪夫迈·罗氏有限公司 | 2021-03-16 | — | — | CN | claimed |