Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | C5 | P01031 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 10/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 10/20 | 0.43 |
| ▸ | CDC42 | P60953 | 1/20 | 0.43 |
| ▸ | RAC1 | P63000 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | FABP6 | P51161 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | MASP2 | O00187 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11252692 | 0.88 | FABP6 (0.52) | PTGS2PTGS1MEN1KMT2AABCC4 | |
| SCHEMBL5683519 | 0.81 | FABP6 (0.50) | MEN1KMT2AMAPTFABP6ABL1 | |
| SCHEMBL28410658 | 0.80 | FABP6 (0.49) | MEN1KMT2AMAPTFABP6ABL1 | |
| SCHEMBL29793642 | 0.80 | FABP6 (0.49) | MEN1KMT2AMAPTFABP6ABL1 | |
| SCHEMBL9289735 | 0.75 | FABP6 (0.44) | MEN1KMT2AMAPTFABP6ABL1 | |
| SCHEMBL1870891 | 0.73 | FABP6 (0.55) | MEN1KMT2AFABP6ABL1MASP2 | |
| SCHEMBL725577 | 0.72 | FABP6 (0.50) | MEN1KMT2AMAPTFABP6ABL1 | |
| Hydrochloric Acid SCHEMBL4682527 | 0.72 | FABP6 (0.54) | MEN1KMT2AFABP6ABL1MASP2 | |
| SCHEMBL15457670 | 0.71 | ALDH1A1 (0.46) | MEN1KMT2AMAPTTSHRALDH1A1 | |
| SCHEMBL31370237 | 0.71 | PKM (0.53) | PTGS2PTGS1FABP6ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4316021-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1982-02-16 | — | — | US | disclosed |
| US-4243813-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1981-01-06 | — | — | US | disclosed |
| US-4196125-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1980-04-01 | — | — | US | disclosed |
| US-4118573-A | ANTIVIRAL AGENTS | ELI LILLY AND COMPANY (US) | 1978-10-03 | — | — | US | disclosed |
| US-4018790-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1977-04-19 | — | — | US | disclosed |