Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP6 | P51161 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.47 |
| ▸ | MASP2 | O00187 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | DHFR | P00374 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29793642 | 1.00 | FABP6 (0.49) | FABP6ALDH1A1KMT2ANUDT1MASP2 | |
| SCHEMBL5683519 | 0.88 | FABP6 (0.50) | FABP6ALDH1A1KMT2ANUDT1MASP2 | |
| SCHEMBL28413241 | 0.83 | ALDH1A1 (0.42) | FABP6ALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL11252685 | 0.80 | PTGS2 (0.47) | FABP6ALDH1A1KMT2ANUDT1MASP2 | |
| SCHEMBL9289735 | 0.78 | FABP6 (0.44) | FABP6ALDH1A1KMT2ANUDT1MASP2 | |
| SCHEMBL129665 | 0.74 | FABP6 (0.60) | FABP6ALDH1A1KMT2ANUDT1MASP2 | |
| SCHEMBL5683024 | 0.74 | SCN10A (0.59) | FABP6ALDH1A1KMT2ANUDT1MASP2 | |
| SCHEMBL118057 | 0.74 | MEN1 (0.57) | FABP6ALDH1A1KMT2ANUDT1MASP2 | |
| SCHEMBL29449363 | 0.74 | MEN1 (0.57) | FABP6ALDH1A1KMT2ANUDT1MASP2 | |
| SCHEMBL23800775 | 0.73 | XDH (0.50) | FABP6ALDH1A1KMT2ANUDT1MASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108929263-B | Arylamide Kv2.1 inhibitor and preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2022-07-22 | — | — | CN | disclosed |
| CN-111108092-A | Arylamide Kv2.1 inhibitor and preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2020-05-05 | — | — | CN | disclosed |