Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11256985 | 0.93 | CLK1 (0.57) | CLK1HTTCA1CA2CA9 | |
| SCHEMBL11257686 | 0.88 | TSHR (0.48) | CLK1HTTSMN1; SMN2PIK3CAALDH1A1 | |
| Water SCHEMBL11255627 | 0.87 | TSHR (0.48) | CLK1HTTSMN1; SMN2PIK3CAALDH1A1 | |
| SCHEMBL11252940 | 0.82 | CLK1 (0.56) | CLK1HTTCA1CA2CA9 | |
| SCHEMBL11258511 | 0.81 | L3MBTL1 (0.53) | CLK1HTTSMN1; SMN2PIK3CAALDH1A1 | |
| SCHEMBL11265331 | 0.80 | KDM4E (0.62) | CLK1HTTSMN1; SMN2PIK3CAALDH1A1 | |
| SCHEMBL11265472 | 0.80 | CLK1 (0.52) | CLK1HTTSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL11257442 | 0.79 | ALDH1A1 (0.71) | CLK1HTTSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL11262482 | 0.79 | KDM4E (0.64) | CLK1HTTSMN1; SMN2PIK3CAALDH1A1 | |
| SCHEMBL11265935 | 0.79 | KDM4E (0.64) | CLK1HTTSMN1; SMN2PIK3CAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |