Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.49 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11247662 | 0.93 | KMT2A (0.59) | LTA4HKMT2AMEN1POLBKCNH2 | |
| Hydrochloric Acid SCHEMBL11253686 | 0.92 | KMT2A (0.58) | LTA4HKMT2AMEN1POLBKCNH2 | |
| SCHEMBL11257999 | 0.90 | MEN1 (0.60) | LTA4HKMT2AMEN1POLBKCNH2 | |
| SCHEMBL11258966 | 0.87 | KDM4E (0.56) | LTA4HKMT2AMEN1KCNH2HTR2A | |
| SCHEMBL11260159 | 0.87 | L3MBTL1 (0.53) | LTA4HKMT2AMEN1POLBKCNH2 | |
| SCHEMBL11250630 | 0.86 | KCNH2 (0.53) | LTA4HKCNH2HRH3HTR2AABCB1 | |
| SCHEMBL11259104 | 0.86 | KCNH2 (0.51) | KMT2AMEN1KCNH2HTR2AABCB1 | |
| SCHEMBL11251375 | 0.83 | ABCB1 (0.54) | LTA4HKMT2AMEN1ALDH1A1ABCB1 | |
| SCHEMBL11251231 | 0.83 | ALDH1A1 (0.60) | KMT2AMEN1KCNH2HRH3ALDH1A1 | |
| SCHEMBL11259087 | 0.83 | KCNH2 (0.58) | KCNH2HTR2AABCB1KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323568-A | INHIBIT PLATELET AGGREGATION | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| EP-0001759-B1 | (OMEGA-AMINOALKOXY) BIBENZYLS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE SUBSTANCES | MITSUBISHI KASEI CORPORATION (JP) | 1981-12-30 | — | — | EP | disclosed |
| US-4220603-A | ANTICOAGULANTS | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1980-09-02 | — | — | US | disclosed |