Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 4/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD5 | P21918 | 1/20 | 0.48 |
| ▸ | HRH2 | P25021 | 1/20 | 0.48 |
| ▸ | HTR1D | P28221 | 1/20 | 0.48 |
| ▸ | HTR1B | P28222 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11259471 | 0.93 | KDM4E (0.53) | ABCB1KDM4EL3MBTL1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11254828 | 0.92 | KDM4E (0.52) | KCNH2ABCB1KDM4EL3MBTL1MEN1 | |
| SCHEMBL11258966 | 0.88 | KDM4E (0.56) | KCNH2HTR2AABCB1KDM4EGRM2 | |
| SCHEMBL11250630 | 0.87 | KCNH2 (0.53) | KCNH2HTR2AABCB1KDM4EGRM2 | |
| SCHEMBL11253483 | 0.86 | LTA4H (0.53) | KCNH2HTR2AABCB1KDM4EGRM2 | |
| SCHEMBL11259087 | 0.84 | KCNH2 (0.58) | KCNH2HTR2AABCB1KDM4ECYP1A2 | |
| SCHEMBL11251231 | 0.84 | ALDH1A1 (0.60) | KCNH2ABCB1KDM4ECYP2D6MEN1 | |
| SCHEMBL11246207 | 0.83 | KDM4E (0.53) | KCNH2HTR2AABCB1KDM4ECYP1A2 | |
| SCHEMBL11256008 | 0.82 | KDM4E (0.52) | ABCB1KDM4EDRD2L3MBTL1MEN1 | |
| SCHEMBL11250779 | 0.82 | KDM4E (0.56) | HTR2AABCB1KDM4ECYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323568-A | INHIBIT PLATELET AGGREGATION | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| EP-0001759-B1 | (OMEGA-AMINOALKOXY) BIBENZYLS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE SUBSTANCES | MITSUBISHI KASEI CORPORATION (JP) | 1981-12-30 | — | — | EP | disclosed |
| US-4220603-A | ANTICOAGULANTS | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1980-09-02 | — | — | US | disclosed |