Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11258869 | 0.86 | ALDH1A1 (0.46) | GAAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL11247027 | 0.81 | TSHR (0.53) | GAATSHRGLAMEN1KMT2A | |
| SCHEMBL11269770 | 0.81 | CYP19A1 (0.43) | MEN1KMT2AALDH1A1MAPTNPC1 | |
| SCHEMBL11253949 | 0.80 | CYP3A4 (0.49) | MEN1KMT2AALDH1A1HTTMAPT | |
| SCHEMBL11244165 | 0.75 | HTT (0.43) | GAAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL11250566 | 0.74 | SMN1; SMN2 (0.40) | GAATSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL11264998 | 0.74 | SMN1; SMN2 (0.40) | GAATSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL11254618 | 0.74 | IMPDH2 (0.64) | GAAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11056203 | 0.74 | NPC1 (0.49) | GAAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL11053847 | 0.74 | HTT (0.49) | GAAMEN1KMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4326074-A | ANTIDIARRHEA AGENTS | WILLIAM H. RORER, INC. (US) | 1982-04-20 | — | — | US | disclosed |