Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PPIA | P62937 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.39 |
| ▸ | CTSV | O60911 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11245263 | 0.89 | C5AR1 (0.52) | CYP19A1HPGDKDM4EALDH1A1PPIA | |
| SCHEMBL11254295 | 0.82 | SGMS2 (0.47) | CYP19A1KDM4EPPIABRD4SGMS2 | |
| SCHEMBL11265930 | 0.81 | C5AR1 (0.43) | CYP19A1HPGDALDH1A1BRD4SGMS2 | |
| SCHEMBL11254409 | 0.81 | GAA (0.41) | HPGDKDM4EALDH1A1LMNANPC1 | |
| SCHEMBL11258028 | 0.81 | C5AR1 (0.41) | CYP19A1HPGDPPIABRD4SGMS2 | |
| SCHEMBL11280329 | 0.80 | C5AR1 (0.47) | KDM4ESGMS2C5AR1 | |
| SCHEMBL11284130 | 0.79 | CYP19A1 (0.44) | CYP19A1HPGDBRD4SGMS2LMNA | |
| SCHEMBL7167350 | 0.78 | PPIA (0.47) | KDM4EPPIABRD4SGMS2C5AR1 | |
| SCHEMBL11275038 | 0.76 | C5AR1 (0.47) | MEN1KMT2AC5AR1 | |
| SCHEMBL11275041 | 0.76 | C5AR1 (0.47) | MEN1KMT2AC5AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4326074-A | ANTIDIARRHEA AGENTS | WILLIAM H. RORER, INC. (US) | 1982-04-20 | — | — | US | disclosed |