Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.32 |
| ▸ | PDE6D | O43924 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | PDE6A | P16499 | 1/20 | 0.31 |
| ▸ | PDE6G | P18545 | 1/20 | 0.31 |
| ▸ | PDE6B | P35913 | 1/20 | 0.31 |
| ▸ | PDE6C | P51160 | 1/20 | 0.31 |
| ▸ | PDE6H | Q13956 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11246911 | 0.90 | HTR2A (0.31) | — | |
| SCHEMBL11246024 | 0.86 | PDE3B (0.33) | PDE5APDE3BPDE3A | |
| SCHEMBL11252299 | 0.85 | XDH (0.33) | PDE5APDE3BPDE3A | |
| SCHEMBL11255145 | 0.84 | PDE5A (0.33) | NR1H2LRRK2TRPV1PDE6DPDE5A | |
| SCHEMBL11243215 | 0.84 | TRPA1 (0.33) | PDE3BPDE3A | |
| SCHEMBL11252931 | 0.84 | TRPA1 (0.36) | LRRK2PDE5AS1PR1PDE3BPDE3A | |
| SCHEMBL11250185 | 0.82 | PDE3B (0.31) | PDE3BPDE3A | |
| SCHEMBL11252271 | 0.82 | POLB (0.36) | PDE3BPDE3A | |
| SCHEMBL11260537 | 0.81 | GPR119 (0.33) | TRPV1 | |
| SCHEMBL11248725 | 0.81 | PDE3B (0.33) | PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4314844-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1982-02-09 | — | — | US | disclosed |