Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 3/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | ADK | P55263 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11250186 | 0.89 | PTGDR2 (0.43) | CNR2ROCK2ROCK1OPRM1OPRD1 | |
| SCHEMBL11261717 | 0.84 | NPSR1 (0.44) | HTR2BNPSR1MAPTPTGDR2ALDH1A1 | |
| SCHEMBL11257859 | 0.84 | JAK2 (0.41) | NPSR1TP53GAAMAPTALDH1A1 | |
| SCHEMBL11248945 | 0.84 | IDO1 (0.42) | PTGDR2ALDH1A1HTT | |
| SCHEMBL11254978 | 0.78 | SYK (0.35) | TP53GAAMAPTSYKADK | |
| SCHEMBL11257961 | 0.77 | KDM4E (0.42) | TP53MAPTPTGDR2ALDH1A1 | |
| SCHEMBL11246786 | 0.74 | LMNA (0.48) | NPSR1GAAMAPTPTGDR2ALDH1A1 | |
| SCHEMBL11251835 | 0.73 | TDP1 (0.54) | HTR2BMAPTPTGDR2ALDH1A1 | |
| SCHEMBL11257643 | 0.73 | PSEN1 (0.39) | CNR2ROCK2ROCK1HTR2CHTR2B | |
| SCHEMBL11262913 | 0.73 | ALDH1A1 (0.39) | CNR2ROCK2ROCK1HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337256-A | ANTIINFLAMMATORY AGENTS; ANTIAGGLOMERANTS; ENZYME INHIBITORS; ANTIULCER AGENTS | TEIKOKU HORMONE MANUFACTURING CO., LTD. (JP) | 1982-06-29 | — | — | US | disclosed |
| EP-0013411-A1 | Isoquinoline derivatives, process for their preparation and pharmaceutical compositions containing them | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1980-07-23 | — | — | EP | disclosed |