Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11255704 | 0.88 | PTGDR2 (0.49) | IDO1TDO2CSNK2A2CSNK2BPTGDR2 | |
| SCHEMBL11261717 | 0.88 | NPSR1 (0.44) | TDO2PTGDR2PDE3BPDE3AKDM4E | |
| SCHEMBL11255165 | 0.84 | CNR2 (0.38) | PTGDR2ALDH1A1HTT | |
| SCHEMBL11266566 | 0.84 | KDR (0.40) | IDO1TDO2CSNK2A2CSNK2BPTGDR2 | |
| SCHEMBL11500393 | 0.83 | PTGDR2 (0.45) | IDO1TDO2CSNK2A2CSNK2BPTGDR2 | |
| SCHEMBL11262405 | 0.80 | TDO2 (0.48) | IDO1TDO2CSNK2A2CSNK2BPTGDR2 | |
| SCHEMBL11253962 | 0.80 | TDO2 (0.45) | IDO1TDO2CSNK2A2CSNK2BPTGDR2 | |
| SCHEMBL11256404 | 0.79 | TDO2 (0.47) | IDO1TDO2CSNK2A2CSNK2BPTGDR2 | |
| SCHEMBL11251835 | 0.76 | TDP1 (0.54) | TDO2PTGDR2PDE3BPDE3AKDM4E | |
| SCHEMBL11248931 | 0.76 | TDO2 (0.44) | IDO1TDO2CSNK2A2CSNK2BPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337256-A | ANTIINFLAMMATORY AGENTS; ANTIAGGLOMERANTS; ENZYME INHIBITORS; ANTIULCER AGENTS | TEIKOKU HORMONE MANUFACTURING CO., LTD. (JP) | 1982-06-29 | — | — | US | disclosed |
| EP-0013411-A1 | Isoquinoline derivatives, process for their preparation and pharmaceutical compositions containing them | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1980-07-23 | — | — | EP | disclosed |