Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.45 |
| ▸ | GABRE | P78334 | 1/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.45 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.45 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.45 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2443191 | 0.81 | ALDH1A1 (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL18365929 | 0.80 | KMT2A (0.45) | KMT2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL15844832 | 0.76 | GABRP (0.42) | KMT2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL11263067 | 0.76 | LMNA (0.40) | KMT2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL8541158 | 0.75 | ALDH1A1 (0.47) | KMT2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL8541938 | 0.75 | ALDH1A1 (0.50) | KMT2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL29746814 | 0.74 | EGLN1 (0.54) | KMT2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL29489052 | 0.74 | EGLN1 (0.54) | KMT2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL155043 | 0.74 | EGLN1 (0.54) | KMT2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL4021192 | 0.74 | PDPK1 (0.57) | KMT2ALMNACYP3A4CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4363909-A | ANTIVIRAL AGENTS | RHONE POULENC INDUSTRIES (FR) | 1982-12-14 | — | — | US | disclosed |