Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.76 |
| ▸ | P2RX7 | Q99572 | 17/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1780230 | 0.87 | TSHR (0.62) | TSHRP2RX7NPC1RAB9AMEN1 | |
| SCHEMBL1779853 | 0.87 | TSHR (0.62) | TSHRP2RX7NPC1RAB9AMEN1 | |
| SCHEMBL11243796 | 0.87 | PDE4D (0.63) | TSHRP2RX7NPC1RAB9AMEN1 | |
| SCHEMBL1195590 | 0.85 | NPC1 (0.73) | TSHRP2RX7NPC1RAB9AMEN1 | |
| SCHEMBL11249174 | 0.82 | NPC1 (0.69) | TSHRP2RX7NPC1RAB9AMEN1 | |
| SCHEMBL1194306 | 0.79 | P2RX7 (0.78) | P2RX7 | |
| SCHEMBL11250369 | 0.78 | NPC1 (0.59) | TSHRP2RX7NPC1RAB9AMEN1 | |
| SCHEMBL509141 | 0.78 | GAA (0.64) | P2RX7NPC1 | |
| SCHEMBL17445808 | 0.77 | P2RX7 (0.61) | TSHRP2RX7 | |
| SCHEMBL8512906 | 0.77 | NPC1 (0.62) | TSHRP2RX7NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4325962-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIDYRETICS | BYK-GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-04-20 | — | — | US | disclosed |
| US-4146721-A | ANALGESICS, ANTIINFLAMMATORY AGENTS AND ANTIPYRETICS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1979-03-27 | — | — | US | disclosed |