Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 8/20 | 0.66 |
| ▸ | THRA | P10827 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | RARB | P10826 | 3/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | TACR2 | P21452 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SHBG | P04278 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4457165 | 0.98 | THRB (0.64) | THRBTHRAALDH1A1ELANEKMT2A | |
| SCHEMBL3121871 | 0.98 | THRB (0.64) | THRBTHRAALDH1A1ELANEKMT2A | |
| SCHEMBL239732 | 0.98 | THRB (0.64) | THRBTHRAALDH1A1ELANEKMT2A | |
| SCHEMBL28433166 | 0.98 | THRB (0.64) | THRBTHRAALDH1A1ELANEKMT2A | |
| SCHEMBL12991076 | 0.98 | THRB (0.64) | THRBTHRAALDH1A1ELANEKMT2A | |
| SCHEMBL28438783 | 0.98 | THRB (0.64) | THRBTHRAALDH1A1ELANEKMT2A | |
| SCHEMBL28430652 | 0.98 | THRB (0.64) | THRBTHRAALDH1A1ELANEKMT2A | |
| SCHEMBL27821662 | 0.98 | THRB (0.64) | THRBTHRAALDH1A1ELANEKMT2A | |
| SCHEMBL1401891 | 0.95 | THRB (0.59) | THRBTHRAALDH1A1ELANEKMT2A | |
| SCHEMBL22258838 | 0.94 | THRB (0.59) | THRBTHRAALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7563917-B2 | Silicon compound and a production process for silicon compound | CHISSO CORPORATION (JP) | 2009-07-21 | — | — | US | disclosed |
| US-20070004932-A1 | Silicon compound and a production process for silicon compound | JNC CORPORATION (JP) | 2007-01-04 | — | — | US | disclosed |
| US-4311841-A | REACTION WITH ALDEHYDE, CONDENSATION | PETROLITE CORPORATION (US) | 1982-01-19 | — | — | US | disclosed |
| US-4163646-A | STABILIZERS, IMINES | PETROLITE CORPORATION (US) | 1979-08-07 | — | — | US | disclosed |
| US-4040799-A | STABILIZERS | PETROLITE CORPORATION (US) | 1977-08-09 | — | — | US | disclosed |
| US-3936279-A | DISTILLATE | PETROLITE CORPORATION (US) | 1976-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004932-A1 | Silicon compound and a production process for silicon compound | STS, SMS, SRM | THRB 1505/4885THRA 822/4885ALDH1A1 1549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.