Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 2/20 | 0.35 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11270915 | 0.99 | HTR2C (0.40) | HTR2CRAD52HCRTR1HCRTR2RAB9A | |
| SCHEMBL11271015 | 0.99 | HTR2C (0.40) | HTR2CRAD52HCRTR1HCRTR2RAB9A | |
| Hydrochloric Acid SCHEMBL11273062 | 0.97 | RAD52 (0.41) | HTR2CRAD52HCRTR1HCRTR2RAB9A | |
| SCHEMBL11254540 | 0.80 | HTR2C (0.45) | HTR2CRAD52RAB9AHTTNPC1 | |
| SCHEMBL11256909 | 0.74 | ALDH1A1 (0.39) | HTR2CRAD52RAB9ANPC1PKM | |
| SCHEMBL11256677 | 0.73 | HTR2C (0.42) | HTR2CRAD52RAB9AHTTNPC1 | |
| SCHEMBL11253928 | 0.73 | HTR2C (0.40) | HTR2CRAD52RAB9AHTTNPC1 | |
| SCHEMBL11270188 | 0.73 | ALDH1A1 (0.41) | HTR2CRAD52RAB9ANPC1PKM | |
| SCHEMBL11264141 | 0.71 | HTR2C (0.43) | HTR2CRAD52RAB9AHTTNPC1 | |
| SCHEMBL11256894 | 0.71 | KMT2A (0.37) | HTR2CRAD52RAB9ANPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |