Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 5/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11253480 | 1.00 | ALDH1A1 (0.41) | ALDH1A1LMNAHPGDMAOBMAOA | |
| SCHEMBL11256909 | 0.99 | ALDH1A1 (0.39) | ALDH1A1LMNAHPGDMAOBMAOA | |
| SCHEMBL11265289 | 0.93 | HTR2C (0.40) | ALDH1A1LMNAHPGDMAOBMAOA | |
| SCHEMBL11255522 | 0.77 | HTR2C (0.39) | ALDH1A1LMNAHPGDHTR2CNPC1 | |
| SCHEMBL11271015 | 0.74 | HTR2C (0.40) | ALDH1A1HPGDMEN1KMT2AHTR2C | |
| SCHEMBL11270915 | 0.74 | HTR2C (0.40) | ALDH1A1HPGDMEN1KMT2AHTR2C | |
| SCHEMBL11255763 | 0.74 | HTR2C (0.41) | ALDH1A1HPGDMEN1KMT2AHTR2C | |
| SCHEMBL11265349 | 0.74 | MGLL (0.39) | ALDH1A1LMNAHPGDMAOBMAOA | |
| Hydrochloric Acid SCHEMBL11273062 | 0.73 | RAD52 (0.41) | ALDH1A1HPGDMEN1KMT2AHTR2C | |
| SCHEMBL11255635 | 0.73 | HTR2C (0.41) | ALDH1A1HPGDMEN1KMT2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |