Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 13/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 11/20 | 0.41 |
| ▸ | NPC1 | O15118 | 11/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11256677 | 0.85 | HTR2C (0.42) | RAB9ASMN1; SMN2NPC1ALDH1A1TP53 | |
| SCHEMBL11258414 | 0.81 | CASP2 (0.64) | CASP2RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL4493348 | 0.79 | CASP2 (0.55) | CASP2RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL11259076 | 0.78 | SMN1; SMN2 (0.41) | RAB9ASMN1; SMN2NPC1ALDH1A1TP53 | |
| SCHEMBL4488390 | 0.77 | CASP2 (0.66) | CASP2RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL11255668 | 0.76 | RAB9A (0.42) | CASP2RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL11264141 | 0.75 | HTR2C (0.43) | RAB9ASMN1; SMN2NPC1ALDH1A1TP53 | |
| SCHEMBL11257864 | 0.74 | CASP2 (0.56) | CASP2RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11255073 | 0.74 | RAD52 (0.44) | RAB9ASMN1; SMN2NPC1ALDH1A1TP53 | |
| SCHEMBL11256191 | 0.73 | HDAC6 (0.38) | RAB9ASMN1; SMN2NPC1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |