Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | CLK1 | P49759 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11261947 | 0.85 | DRD2 (0.54) | ALDH1A1POLBCLK1HTTSMN1; SMN2 | |
| SCHEMBL11254394 | 0.85 | PKM (0.59) | CLK1L3MBTL1 | |
| SCHEMBL11256985 | 0.81 | CLK1 (0.57) | ALDH1A1POLBCLK1HTTSMN1; SMN2 | |
| SCHEMBL11270275 | 0.81 | SLC27A1 (0.69) | ALDH1A1POLBCLK1HTTSMN1; SMN2 | |
| SCHEMBL11265331 | 0.79 | KDM4E (0.62) | ALDH1A1POLBCLK1HTTSMN1; SMN2 | |
| SCHEMBL11262482 | 0.78 | KDM4E (0.64) | ALDH1A1POLBCLK1HTTSMN1; SMN2 | |
| SCHEMBL11265935 | 0.78 | KDM4E (0.64) | ALDH1A1POLBCLK1HTTSMN1; SMN2 | |
| SCHEMBL11254392 | 0.77 | SMN1; SMN2 (0.43) | ALDH1A1POLBCLK1HTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11254026 | 0.77 | KDM4E (0.63) | ALDH1A1POLBCLK1HTTSMN1; SMN2 | |
| SCHEMBL11265830 | 0.77 | CLK1 (0.58) | ALDH1A1POLBCLK1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |