Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.53 |
| ▸ | RHEB | Q15382 | 3/20 | 0.47 |
| ▸ | KMO | O15229 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.44 |
| ▸ | BAX | Q07812 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25960524 | 0.86 | LTA4H (0.53) | LTA4HRHEBKMONR1H2NR1H3 | |
| SCHEMBL11185908 | 0.84 | LTA4H (0.44) | LTA4HKMONR1H2BAXPGR | |
| SCHEMBL3532436 | 0.82 | DPP4 (0.49) | LTA4HKMOPGRTSHRMAOB | |
| SCHEMBL10836783 | 0.82 | PGR (0.43) | LTA4HKMONR1H2BAXPGR | |
| SCHEMBL994959 | 0.82 | HTR2A (0.52) | LTA4HKMOPGRTSHR | |
| SCHEMBL2093112 | 0.80 | LTA4H (0.55) | LTA4HNR1H2BAXTSHRGSTP1 | |
| SCHEMBL5784934 | 0.79 | LTA4H (0.53) | LTA4HRHEBNR1H2BAXTSHR | |
| SCHEMBL20439168 | 0.79 | LTA4H (0.53) | LTA4HNR1H2BAXTSHRGSTP1 | |
| SCHEMBL11391950 | 0.79 | LTA4H (0.53) | LTA4HRHEBNR1H2BAXTSHR | |
| SCHEMBL6184207 | 0.79 | LTA4H (0.53) | LTA4HNR1H2BAXTSHRGSTP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2668191-A2 | BENZOFURO[3,2-C]PYRIDINES AND RELATED ANALOGS AS SEROTONIN SUB-TYPE 6 (5-HT6) MODULATORS FOR THE TREATMENT OF OBESITY, METABOLIC SYNDROME, COGNITION AND SCHIZOPHRENIA | Albany Molecular Research, Inc. (US) | 2013-12-04 | — | — | EP | disclosed |
| WO-2012099952-A2 | BENZOFURO[3,2-C] PYRIDINES AND RELATED ANALOGS AS SEROTONIN SUB-TYPE 6 (5-HT6) MODULATORS FOR THE TREATMENT OF OBESITY, METABOLIC SYNDROME, COGNITION AND SCHIZOPHRENIA | ALBANY MOLECULAR RESEARCH, INC. (US) | 2012-07-26 | — | — | WO | disclosed |
| US-4366325-A | Process for the preparation of 3-phenoxy-benzaldehydes | BAYER AKTIENGESELLSCHAFT (DE) | 1982-12-28 | — | — | US | disclosed |
| EP-0028714-B1 | PROCESS FOR THE PREPARATION OF 3-PHENOXYBENZALDEHYDES | BAYER AG (DE) | 1982-09-15 | — | — | EP | disclosed |
| EP-0028714-A1 | Process for the preparation of 3-phenoxybenzaldehydes | BAYER AG (DE) | 1981-05-20 | — | — | EP | disclosed |