Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.53 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | BAX | Q07812 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.42 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.42 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19454753 | 0.87 | KMT2A (0.49) | TDP1L3MBTL1NPC1MEN1KMT2A | |
| SCHEMBL19427261 | 0.86 | LTA4H (0.53) | LTA4HNR1H2BAXTSHRGAA | |
| SCHEMBL15186253 | 0.84 | LTA4H (0.50) | LTA4HTSHRGSTP1SRD5A2NPC1 | |
| SCHEMBL8259798 | 0.81 | LTA4H (0.49) | LTA4HTSHRTDP1L3MBTL1NPC1 | |
| SCHEMBL2093112 | 0.80 | LTA4H (0.55) | LTA4HNR1H2BAXTSHRGSTP1 | |
| SCHEMBL5784934 | 0.79 | LTA4H (0.53) | LTA4HNR1H2BAXTSHRGSTP1 | |
| SCHEMBL11391950 | 0.79 | LTA4H (0.53) | LTA4HNR1H2BAXTSHRGSTP1 | |
| SCHEMBL11255857 | 0.79 | LTA4H (0.53) | LTA4HNR1H2BAXTSHRGSTP1 | |
| SCHEMBL6184207 | 0.79 | LTA4H (0.53) | LTA4HNR1H2BAXTSHRGAA | |
| SCHEMBL16319058 | 0.78 | ALOX5 (0.53) | LTA4HGSTP1TDP1L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018140186-A1 | A PROCESS FOR PREPARING 5-PHENOXY-1(3H)ISOBENZOFURANONE | KINGCHEM LIFE SCIENCE LLC (US) | 2018-08-02 | — | — | WO | disclosed |