Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.31 |
| ▸ | FEN1 | P39748 | 2/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11251508 | 0.97 | CAMKK2 (0.36) | CAMKK2CXCR2NPC1ALDH1A1MAPT | |
| SCHEMBL11251784 | 0.96 | CAMKK2 (0.35) | CAMKK2CXCR2ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11261376 | 0.78 | KDM4E (0.41) | CDK5NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL11260207 | 0.77 | TDP1 (0.35) | CDK5 | |
| SCHEMBL11267832 | 0.77 | TDP1 (0.45) | CAMKK2CCNE1CDK2CDK5MAPT | |
| SCHEMBL11251670 | 0.74 | ELANE (0.40) | — | |
| SCHEMBL11269174 | 0.74 | TDP1 (0.45) | CAMKK2CCNE1CDK2CDK5MAPT | |
| SCHEMBL11252606 | 0.73 | TDP1 (0.44) | CAMKK2CCNE1CDK2CDK5MAPT | |
| SCHEMBL21617927 | 0.73 | ALDH1A1 (0.45) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11266460 | 0.72 | CDK5 (0.38) | CAMKK2CCNE1CDK2CDK5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337256-A | ANTIINFLAMMATORY AGENTS; ANTIAGGLOMERANTS; ENZYME INHIBITORS; ANTIULCER AGENTS | TEIKOKU HORMONE MANUFACTURING CO., LTD. (JP) | 1982-06-29 | — | — | US | disclosed |
| EP-0013411-A1 | Isoquinoline derivatives, process for their preparation and pharmaceutical compositions containing them | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1980-07-23 | — | — | EP | disclosed |