Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 2/20 | 0.31 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097402 | 0.82 | SMN1; SMN2 (0.36) | SMN1; SMN2ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL8097337 | 0.77 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL11383008 | 0.75 | ALDH1A1 (0.31) | ALDH1A1TSHR | |
| SCHEMBL9169273 | 0.74 | ALDH1A1 (0.42) | SMN1; SMN2ALDH1A1LMNATSHRGAA | |
| SCHEMBL11254150 | 0.73 | ANO1 (0.32) | ANO1 | |
| SCHEMBL11256352 | 0.73 | LMNA (0.32) | LMNA | |
| SCHEMBL7213661 | 0.72 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL9510245 | 0.70 | ALDH1A1 (0.35) | ALDH1A1TSHR | |
| SCHEMBL10809433 | 0.69 | — | — | |
| SCHEMBL7220027 | 0.68 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1KDM4EHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4335053-A | HERBICIDES | STAUFFER CHEMICAL COMPANY (US) | 1982-06-15 | — | — | US | disclosed |
| US-4288384-A | N-Cyanoalkyl haloacetamides herbicidal antidotes | STAUFFER CHEMICAL COMPANY (US) | 1981-09-08 | — | — | US | disclosed |
| EP-0025345-A1 | N-cyanoalkyl haloacetamides, preparation thereof, use thereof as herbicide antidotes and compositions comprising same | STAUFFER CHEMICAL COMPANY (US) | 1981-03-18 | — | — | EP | disclosed |