Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 2/20 | 0.32 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097402 | 0.82 | SMN1; SMN2 (0.36) | SMN1; SMN2DPP4CTSSCTSKKDM4E | |
| SCHEMBL7213661 | 0.79 | SMN1; SMN2 (0.39) | SMN1; SMN2DPP4CTSSCTSKKDM4E | |
| SCHEMBL11256255 | 0.77 | SMN1; SMN2 (0.39) | SMN1; SMN2DPP4CTSSCTSKKDM4E | |
| SCHEMBL7220027 | 0.74 | SMN1; SMN2 (0.45) | SMN1; SMN2DPP4KDM4EALDH1A1LMNA | |
| SCHEMBL23084588 | 0.73 | POLB (0.46) | KDM4EALDH1A1KMT2A | |
| SCHEMBL8229637 | 0.73 | POLB (0.46) | KDM4EALDH1A1KMT2A | |
| SCHEMBL8222052 | 0.73 | POLB (0.46) | KDM4EALDH1A1KMT2A | |
| SCHEMBL7220925 | 0.72 | POLB (0.36) | SMN1; SMN2DPP4LMNAKMT2A | |
| SCHEMBL7219260 | 0.71 | ANO1 (0.42) | ANO1 | |
| SCHEMBL8106282 | 0.71 | CTSK (0.40) | SMN1; SMN2CTSSCTSKLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090815-A | Pyrimidinyloxyalkanoic amide derivatives and fungicides for agricultural and horticultural use | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2000-07-18 | — | — | US | disclosed |
| EP-0940392-A1 | PYRIMIDINYLOXYALKANOIC AMIDE DERIVATIVES AND FUNGICIDES FOR AGRICULTURAL AND HORTICULTURAL USE | KumaiI Chemical Industry Co., Ltd. (JP) | 1999-09-08 | — | — | EP | disclosed |