Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 2/20 | 0.41 |
| ▸ | FOS | P01100 | 1/20 | 0.41 |
| ▸ | JUN | P05412 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6573972 | 0.87 | LDHA (0.58) | ALDH1A1HTTLDHATTRFOS | |
| SCHEMBL11595544 | 0.74 | CA2 (0.39) | GAAMEN1MAPTKMT2A | |
| SCHEMBL3315101 | 0.74 | ALDH1A1 (0.61) | ALDH1A1HTTTDP1LDHACYP3A4 | |
| SCHEMBL1094491 | 0.74 | LDHA (0.56) | ALDH1A1TDP1LDHAHSD17B10MEN1 | |
| SCHEMBL1094489 | 0.74 | LDHA (0.56) | ALDH1A1TDP1LDHAHSD17B10MEN1 | |
| SCHEMBL4096678 | 0.71 | ALDH1A1 (0.71) | ALDH1A1HTTTDP1CYP3A4TSHR | |
| SCHEMBL31045431 | 0.71 | ALDH1A1 (0.71) | ALDH1A1HTTTDP1CYP3A4TSHR | |
| SCHEMBL27952504 | 0.71 | TSHR (0.57) | ALDH1A1HTTTDP1TSHRLMNA | |
| SCHEMBL30541678 | 0.70 | ALDH1A1 (1.00) | ALDH1A1HTTTDP1CYP3A4TSHR | |
| SCHEMBL273470 | 0.70 | ALDH1A1 (1.00) | ALDH1A1HTTTDP1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4361516-A | N-Monosubstituted indoanilines | SOCIETE ANONYME DITE: L'OREAL (FR) | 1982-11-30 | — | — | US | disclosed |