Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11271655 | 0.86 | HDAC1 (0.51) | HDAC1HDAC6ALOX15ALDH1A1L3MBTL1 | |
| SCHEMBL11267916 | 0.82 | CAPN1 (0.48) | RAB9AHDAC1HDAC6POLBALOX15 | |
| SCHEMBL11256499 | 0.80 | NPSR1 (0.49) | HDAC1HDAC6POLBALOX15ALDH1A1 | |
| SCHEMBL8726366 | 0.79 | PLA2G10 (0.56) | HDAC1HDAC6POLBALOX15ALDH1A1 | |
| SCHEMBL11265232 | 0.78 | PLA2G10 (0.48) | HDAC1HDAC6POLBALOX15ALDH1A1 | |
| SCHEMBL11266748 | 0.78 | L3MBTL1 (0.42) | HDAC1HDAC6POLBALOX15ALDH1A1 | |
| SCHEMBL11262289 | 0.77 | CYP3A4 (0.43) | ALOX15 | |
| SCHEMBL11263373 | 0.77 | KMT2A (0.52) | HDAC1HDAC6POLBALOX15ALDH1A1 | |
| SCHEMBL4577007 | 0.76 | HDAC6 (0.49) | RAB9AHDAC1HDAC6CYP4A11LOXL2 | |
| SCHEMBL11262980 | 0.75 | ALDH1A1 (0.43) | HDAC1HDAC6POLBALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005647-B1 | HYDANTOIN COMPOUNDS, THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM | Lilly Industries Limited (GB) | 1982-06-09 | — | — | EP | disclosed |
| US-4293563-A | ANTIASTHMATICS | LILLY INDUSTRIES LIMITED (GB) | 1981-10-06 | — | — | US | disclosed |
| US-4241073-A | ASTHMA | LILLY INDUSTRIES LIMITED (GB) | 1980-12-23 | — | — | US | disclosed |