Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | TBXAS1 | P24557 | 7/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9266704 | 0.90 | TBXAS1 (0.70) | ALDH1A1MAPTTSHRCYP19A1MEN1 | |
| SCHEMBL9264092 | 0.90 | TBXAS1 (0.70) | ALDH1A1MAPTTSHRCYP19A1MEN1 | |
| SCHEMBL11261752 | 0.86 | ALDH1A1 (0.64) | ALDH1A1MAPTTSHRCYP19A1MEN1 | |
| SCHEMBL8021758 | 0.86 | CYP19A1 (0.69) | ALDH1A1MAPTTSHRCYP19A1 | |
| Bromide SCHEMBL27662645 | 0.84 | CYP19A1 (0.67) | ALDH1A1MAPTTSHRCYP19A1 | |
| Hydrochloric Acid SCHEMBL410723 | 0.84 | CYP19A1 (0.67) | ALDH1A1MAPTTSHRCYP19A1 | |
| SCHEMBL11257445 | 0.84 | TBXAS1 (0.58) | ALDH1A1CYP19A1KMT2ATBXAS1 | |
| SCHEMBL11153260 | 0.84 | TBXAS1 (0.62) | CYP19A1MEN1KMT2ATBXAS1LMNA | |
| SCHEMBL11154431 | 0.83 | PKM (0.52) | MEN1KMT2ATBXAS1LMNA | |
| SCHEMBL9850492 | 0.82 | TBXAS1 (0.56) | ALDH1A1CYP19A1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709378-B1 | Aminoalkyloximes, a process for their preparation, their use as medicaments and intermediate compounds | AVENTIS PHARMA INC (US) | 2003-03-19 | — | — | EP | disclosed |
| US-5696142-A | TREATING DEPRESSION, OBSESSIVE COMPULSIVE DISORDERS | HOECHST MARION ROUSSEL, INC. (US) | 1997-12-09 | — | — | US | disclosed |
| US-5686447-A | ANTIDEPRESSANTS, OBSESSIVE COMPULSIVE DISORDERS | HOECHST MARION ROUSSEL, INC. (US) | 1997-11-11 | — | — | US | disclosed |
| US-5686483-A | TREATING DEPRESSION AND OBSESSIVE COMPULSIVE DISORDERS | HOECHST MARION ROUSSEL, INC. (US) | 1997-11-11 | — | — | US | disclosed |
| US-5686446-A | ANTIDEPRESSANTS, OBSESSIVE COMPULSIVE DISORDERS | HOECHST MARION ROUSSEL, INC. (US) | 1997-11-11 | — | — | US | disclosed |
| US-5684021-A | Aminoalkyloximes for treating depression and affective disorders | HOECHST MARION ROUSSEL, INC. (US) | 1997-11-04 | — | — | US | disclosed |
| US-5665756-A | Aminoalkyloximes useful in the treatment of depression and obsessive compulsive disorders | HOECHST MARION ROUSSEL, INC. (US) | 1997-09-09 | — | — | US | disclosed |
| US-5648367-A | ANTIDEPRESANTS, OBSESSIVE-COMPULSIVE DISORDER | HOECHST MARION ROUSSEL, INC. (US) | 1997-07-15 | — | — | US | disclosed |
| EP-0709378-A2 | Aminoalkyloximes, a process for their preparation, their use as medicaments and intermediate compounds | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1996-05-01 | — | — | EP | disclosed |
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |