Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16030042 | 0.89 | ALDH1A1 (0.62) | EPHX1ALDH1A1SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL9311503 | 0.89 | EPHX1 (0.62) | EPHX1ALDH1A1SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL5443717 | 0.88 | ALDH1A1 (0.84) | EPHX1ALDH1A1SMN1; SMN2LMNANPC1 | |
| SCHEMBL16119691 | 0.87 | EPHX1 (0.60) | EPHX1ALDH1A1SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL14096562 | 0.86 | ALDH1A1 (0.67) | EPHX1ALDH1A1SMN1; SMN2LMNANPC1 | |
| SCHEMBL11170313 | 0.85 | EPHX1 (0.59) | EPHX1ALDH1A1SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL2351309 | 0.85 | ALDH1A1 (0.56) | EPHX1ALDH1A1SMN1; SMN2LMNANPC1 | |
| SCHEMBL8616512 | 0.84 | ALDH1A1 (0.67) | EPHX1ALDH1A1SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL5713527 | 0.84 | EPHX1 (1.00) | EPHX1ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4138460 | 0.83 | POLB (0.67) | SMN1; SMN2LMNANPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10730848-B2 | Protective molecules against anthrax toxin | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-08-04 | — | — | US | disclosed |
| US-10730848-B2 | Protective molecules against anthrax toxin | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-08-04 | — | — | US | disclosed |
| US-20160016930-A1 | PROTECTIVE MOLECULES AGAINST ANTHRAX TOXIN | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-01-21 | — | — | US | disclosed |
| US-20160016930-A1 | PROTECTIVE MOLECULES AGAINST ANTHRAX TOXIN | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-01-21 | — | — | US | disclosed |
| US-20160016930-A1 | PROTECTIVE MOLECULES AGAINST ANTHRAX TOXIN | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-01-21 | — | — | US | disclosed |
| WO-2014113607-A1 | PROTECTIVE MOLECULES AGAINST ANTHRAX TOXIN | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-07-24 | — | — | WO | disclosed |
| WO-2014113607-A1 | PROTECTIVE MOLECULES AGAINST ANTHRAX TOXIN | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-07-24 | — | — | WO | disclosed |
| US-4326074-A | ANTIDIARRHEA AGENTS | WILLIAM H. RORER, INC. (US) | 1982-04-20 | — | — | US | disclosed |
| US-4115564-A | Treatment of diarrhea with amidinoureas | WILLIAM H. RORER, INC. (US) | 1978-09-19 | — | — | US | disclosed |
| US-4025652-A | ANTIDIARRHEA AGENTS | WILLIAM H. RORER, INC. (US) | 1977-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160016930-A1 | PROTECTIVE MOLECULES AGAINST ANTHRAX TOXIN | ANTXR2, TSG101, ANXA1 | EPHX1 1283/4885ALDH1A1 3473/4885SMN1; SMN2 3581/4885 |
| US-10730848-B2 | Protective molecules against anthrax toxin | ANTXR2, TSG101, ANXA1 | EPHX1 1283/4885ALDH1A1 3473/4885SMN1; SMN2 3581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.