Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 3/20 | 0.50 |
| ▸ | IMPDH1 | P20839 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | PYGL | P06737 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11250817 | 0.90 | SMN1; SMN2 (0.55) | IMPDH2IMPDH1HTTMAPTMEN1 | |
| SCHEMBL11254618 | 0.88 | IMPDH2 (0.64) | IMPDH2IMPDH1MAPTMEN1KMT2A | |
| SCHEMBL11055632 | 0.85 | HTT (0.59) | HTTMAPTMEN1KMT2ANPC1 | |
| SCHEMBL11250658 | 0.83 | HTT (0.60) | HTTMAPTMEN1KMT2AMAOB | |
| SCHEMBL11248846 | 0.82 | HTT (0.52) | HTTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL11053290 | 0.82 | HTT (0.52) | IMPDH2HTTMAPTMEN1KMT2A | |
| SCHEMBL11258217 | 0.82 | GRM4 (0.55) | HTTMAPTMEN1KMT2AGRM4 | |
| SCHEMBL11253949 | 0.82 | CYP3A4 (0.49) | IMPDH2IMPDH1HTTMAPTMEN1 | |
| SCHEMBL11252801 | 0.81 | HTT (0.77) | HTTMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11054939 | 0.80 | HTT (0.56) | HTTMAPTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4326074-A | ANTIDIARRHEA AGENTS | WILLIAM H. RORER, INC. (US) | 1982-04-20 | — | — | US | disclosed |