Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | AR | P10275 | 2/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PYGL | P06737 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11252801 | 0.89 | HTT (0.77) | HTTSLC2A1MEN1KMT2ANPC1 | |
| SCHEMBL11055632 | 0.89 | HTT (0.59) | HTTSLC2A1POLBMEN1KMT2A | |
| SCHEMBL11249445 | 0.87 | HTT (0.57) | HTTARPOLBMEN1KMT2A | |
| SCHEMBL11248846 | 0.85 | HTT (0.52) | HTTARSLC2A1POLBMEN1 | |
| SCHEMBL11053290 | 0.85 | HTT (0.52) | HTTARSLC2A1ANO1POLB | |
| SCHEMBL11257942 | 0.84 | HTT (0.58) | HTTARPOLBMEN1KMT2A | |
| SCHEMBL11261746 | 0.84 | HTT (0.50) | HTTARMEN1KMT2AMAPK1 | |
| SCHEMBL11244605 | 0.84 | HTT (0.50) | HTTARANO1MEN1KMT2A | |
| SCHEMBL11255985 | 0.84 | HTT (0.50) | HTTARANO1MEN1KMT2A | |
| SCHEMBL11258017 | 0.83 | IMPDH2 (0.50) | HTTPOLBMEN1KMT2APYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4326074-A | ANTIDIARRHEA AGENTS | WILLIAM H. RORER, INC. (US) | 1982-04-20 | — | — | US | disclosed |