Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 10/20 | 0.72 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.53 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.53 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.53 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.53 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.53 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.53 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.53 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.53 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11258739 | 0.87 | ADORA3 (0.74) | ADORA3GRIN2DGRIN3BGRIA1GRIA2 | |
| SCHEMBL11250907 | 0.86 | ADORA3 (0.72) | ADORA3GRIN2DGRIN3BGRIA1GRIA2 | |
| SCHEMBL11255156 | 0.86 | ADORA3 (0.76) | ADORA3GRIN2DGRIN3BGRIA1GRIA2 | |
| Acetone SCHEMBL11543246 | 0.85 | ADORA3 (0.74) | ADORA3GRIN2DGRIN3BGRIA1GRIA2 | |
| SCHEMBL11544907 | 0.84 | ADORA3 (0.69) | ADORA3GRIN2DGRIN3BGRIA1GRIA2 | |
| Acetaldehyde SCHEMBL11543250 | 0.82 | ADORA3 (0.70) | ADORA3GRIN2DGRIN3BGRIA1GRIA2 | |
| SCHEMBL11631304 | 0.80 | ADORA3 (0.67) | ADORA3 | |
| SCHEMBL11631308 | 0.80 | ADORA3 (0.67) | ADORA3 | |
| SCHEMBL11266931 | 0.80 | ADORA3 (1.00) | ADORA3 | |
| SCHEMBL9036763 | 0.77 | ADORA3 (0.67) | ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337255-A | ANTI-ALLERGY AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1982-06-29 | — | — | US | disclosed |
| US-4179561-A | REACTING A 3-DIAZOOXINDOLE WITH A SUBSTITUTED ACETYLENE | E. R. SQUIBB & SONS, INC. (US) | 1979-12-18 | — | — | US | disclosed |
| US-4164578-A | ANTIALLERGENS | E. R. SQUIBB & SONS, INC. (US) | 1979-08-14 | — | — | US | disclosed |
| US-4145420-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1979-03-20 | — | — | US | disclosed |
| US-4128644-A | ANTIALLERGENS, ANTIINFLAMMATORY PHOSPHODIESTERASE INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1978-12-05 | — | — | US | disclosed |
| US-4112096-A | ANTIALLERGENS | E. R. SQUIBB & SONS, INC. (US) | 1978-09-05 | — | — | US | disclosed |
| US-4076818-A | ANTIALLERGENS | E. R. SQUIBB & SONS, INC. (US) | 1978-02-28 | — | — | US | disclosed |