Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 10/20 | 0.74 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.65 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.65 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.65 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.65 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.65 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.65 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.65 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.65 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.65 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.65 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11544907 | 0.88 | ADORA3 (0.69) | ADORA3GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL11258237 | 0.87 | ADORA3 (0.72) | ADORA3GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL11255156 | 0.87 | ADORA3 (0.76) | ADORA3GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL11250907 | 0.87 | ADORA3 (0.72) | ADORA3GRIA1GRIA2GRIA3GRIA4 | |
| Acetone SCHEMBL11543246 | 0.86 | ADORA3 (0.74) | ADORA3GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL11392211 | 0.84 | ADORA3 (0.54) | ADORA3GRIA1GRIA2GRIA3GRIA4 | |
| Acetaldehyde SCHEMBL11543250 | 0.83 | ADORA3 (0.70) | ADORA3GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL11622022 | 0.82 | GRIA1 (0.72) | ADORA3GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL11631304 | 0.81 | ADORA3 (0.67) | ADORA3 | |
| SCHEMBL11631308 | 0.81 | ADORA3 (0.67) | ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4164578-A | ANTIALLERGENS | E. R. SQUIBB & SONS, INC. (US) | 1979-08-14 | — | — | US | claimed |
| US-4123532-A | ADMINISTERING A PYRAZOLO(1,5-C)QUINAZOLIN-5(6H)-ONE COMPOUND | E. R. SQUIBB & SONS, INC. (US) | 1978-10-31 | — | — | US | claimed |
| US-4337255-A | ANTI-ALLERGY AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1982-06-29 | — | — | US | disclosed |
| US-4282226-A | Thioxopyrazolo[1,5-c]quinazoline derivatives, anti-allergic compositions and methods for treating allergic conditions by parenteral administration, aerosol or insufflation | E. R. SQUIBB & SONS, INC. (US) | 1981-08-04 | — | — | US | disclosed |
| US-4179561-A | REACTING A 3-DIAZOOXINDOLE WITH A SUBSTITUTED ACETYLENE | E. R. SQUIBB & SONS, INC. (US) | 1979-12-18 | — | — | US | disclosed |
| US-4164578-A | ANTIALLERGENS | E. R. SQUIBB & SONS, INC. (US) | 1979-08-14 | — | — | US | disclosed |
| US-4145420-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1979-03-20 | — | — | US | disclosed |
| US-4128644-A | ANTIALLERGENS, ANTIINFLAMMATORY PHOSPHODIESTERASE INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1978-12-05 | — | — | US | disclosed |
| US-4123532-A | ADMINISTERING A PYRAZOLO(1,5-C)QUINAZOLIN-5(6H)-ONE COMPOUND | E. R. SQUIBB & SONS, INC. (US) | 1978-10-31 | — | — | US | disclosed |
| US-4112096-A | ANTIALLERGENS | E. R. SQUIBB & SONS, INC. (US) | 1978-09-05 | — | — | US | disclosed |
| US-4076818-A | ANTIALLERGENS | E. R. SQUIBB & SONS, INC. (US) | 1978-02-28 | — | — | US | disclosed |
| US-3903106-A | Pyrazole-3-carboxylic acids | LILLY CO ELI | 1975-09-02 | — | — | US | disclosed |
| US-3895027-A | Process for preparing pyrazole-3-carboxylic acids | LILLY CO ELI | 1975-07-15 | — | — | US | disclosed |