Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 9/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11271136 | 0.83 | OPRM1 (0.33) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL10605630 | 0.76 | DRD3 (0.37) | OPRL1OPRM1OPRK1OPRD1GAA | |
| SCHEMBL11266397 | 0.73 | MAOA (0.36) | OPRL1OPRM1OPRK1APOBEC3AAPOBEC3G | |
| SCHEMBL30516777 | 0.73 | OPRM1 (0.54) | OPRL1OPRM1OPRK1OPRD1CHRM3 | |
| SCHEMBL11155552 | 0.72 | OPRM1 (0.49) | OPRL1OPRM1OPRK1OPRD1CHRM3 | |
| SCHEMBL11150638 | 0.72 | OPRM1 (0.53) | OPRM1 | |
| Hydrochloric Acid SCHEMBL11153301 | 0.71 | OPRM1 (0.47) | OPRL1OPRM1OPRK1OPRD1CHRM3 | |
| SCHEMBL11260236 | 0.70 | ALDH1A1 (0.38) | GAAHTT | |
| SCHEMBL11157863 | 0.69 | OPRM1 (0.51) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL11155466 | 0.66 | CYP2D6 (0.52) | OPRL1OPRM1OPRK1OPRD1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4333942-A | Anti-depressant and analgesic 4-phenoxypiperidines | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-06-08 | — | — | US | disclosed |