SCHEMBL11258797

SCHEMBL11258797

CCCCCCCCCCCCCCCCCCN1C(C)(C)CCCC1(C)C

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 2/20 0.35
GNAO1 P09471 2/20 0.35
GNAI1 P63096 2/20 0.35
S1PR1 P21453 2/20 0.35
S1PR3 Q99500 2/20 0.35
S1PR5 Q9H228 2/20 0.35
TSHR P16473 1/20 0.35
THRB P10828 1/20 0.35
GUSB P08236 2/20 0.34
EBP Q15125 1/20 0.34
SIGMAR1 Q99720 1/20 0.34
S1PR4 O95977 1/20 0.34
ALOX5 P09917 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10170224 1.00 GNAI3 (0.35) GNAI3GNAO1GNAI1S1PR1S1PR3
SCHEMBL7993218 1.00 GNAI3 (0.35) GNAI3GNAO1GNAI1S1PR1S1PR3
SCHEMBL8585081 1.00 GNAI3 (0.35) GNAI3GNAO1GNAI1S1PR1S1PR3
SCHEMBL9839237 0.98 S1PR1 (0.33) GNAI3GNAO1GNAI1S1PR1S1PR3
SCHEMBL5083427 0.91 TSHR (0.32) S1PR1S1PR3S1PR5TSHR
SCHEMBL10171050 0.91 TSHR (0.34) TSHR
SCHEMBL10170323 0.91 TSHR (0.34) TSHR
SCHEMBL10171052 0.91 TSHR (0.34) TSHR
SCHEMBL10170322 0.89 TSHR (0.35) TSHR
SCHEMBL8476820 0.81 TSHR (0.34) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4336183-A 2,2,6,6-Tetramethyl-4-piperidyl carboxylic acid esters and amides of mono and poly alcohols, phenols and amines as stabilizers for synthetic polymers ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1982-06-22 US disclosed
US-3975357-A SUBSTITUTED PIPERIDINES SANKYO COMPANY LIMITED (JA) 1976-08-17 US disclosed