Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | GUSB | P08236 | 2/20 | 0.31 |
| ▸ | EBP | Q15125 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8585081 | 0.98 | GNAI3 (0.35) | S1PR1S1PR3S1PR5GNAI3GNAO1 | |
| SCHEMBL7993218 | 0.98 | GNAI3 (0.35) | S1PR1S1PR3S1PR5GNAI3GNAO1 | |
| SCHEMBL11258797 | 0.98 | GNAI3 (0.35) | S1PR1S1PR3S1PR5GNAI3GNAO1 | |
| SCHEMBL10170224 | 0.98 | GNAI3 (0.35) | S1PR1S1PR3S1PR5GNAI3GNAO1 | |
| SCHEMBL5083427 | 0.93 | TSHR (0.32) | S1PR1S1PR3S1PR5TSHRNFKB1 | |
| SCHEMBL10170322 | 0.91 | TSHR (0.35) | TSHRNFKB1CYP2C19 | |
| SCHEMBL10171050 | 0.88 | TSHR (0.34) | TSHRNFKB1CYP2C19 | |
| SCHEMBL10170323 | 0.88 | TSHR (0.34) | TSHRNFKB1CYP2C19 | |
| SCHEMBL10171052 | 0.88 | TSHR (0.34) | TSHRNFKB1CYP2C19 | |
| SCHEMBL8476820 | 0.83 | TSHR (0.34) | TSHRNFKB1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2284172-A1 | Immunomodulating heterocyclic compounds | MediGene Ltd. (GB) | 2011-02-16 | — | — | EP | disclosed |
| EP-0257321-B1 | IMPROVING WEATHERABILITY AND ADHERENCE OF POLYPROPYLENE | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1991-03-13 | — | — | EP | disclosed |
| US-4997888-A | Tetramethyl piperidyl compound | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1991-03-05 | — | — | US | disclosed |
| US-4994529-A | Surface activation with oxygen; piperidyl stabilizer and phenolic antioxidant present | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1991-02-19 | — | — | US | disclosed |
| EP-0257321-A2 | Improving weatherability and adherence of polypropylene | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1988-03-02 | — | — | EP | disclosed |