Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11814304 | 0.79 | MAPT (0.41) | HSD17B10KDM4EALDH1A1TSHRCA1 | |
| SCHEMBL9359773 | 0.78 | TSHR (0.48) | HSD17B10KDM4EALDH1A1TSHRCA1 | |
| SCHEMBL2142613 | 0.78 | PPARG (0.48) | HSD17B10KDM4EALDH1A1TSHRCES1 | |
| SCHEMBL2033994 | 0.75 | CES1 (0.52) | HSD17B10ALDH1A1TSHRCA1CA2 | |
| SCHEMBL11246495 | 0.74 | TSHR (0.54) | HSD17B10KDM4EALDH1A1TSHRMAPT | |
| SCHEMBL28761122 | 0.74 | TSHR (0.44) | HSD17B10KDM4EALDH1A1TSHRCA1 | |
| SCHEMBL10090157 | 0.74 | CES1 (0.60) | HSD17B10KDM4EALDH1A1TSHRCES1 | |
| SCHEMBL1805490 | 0.73 | CA2 (0.56) | HSD17B10KDM4EALDH1A1TSHRCA1 | |
| SCHEMBL10385943 | 0.73 | CES1 (0.46) | HSD17B10ALDH1A1TSHRTP53CES1 | |
| SCHEMBL11251806 | 0.73 | CES1 (0.46) | HSD17B10KDM4EALDH1A1TSHRCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4321118-A | Bis benzoyl sensitizers for photopolymerization or photo cross linking process and composition | CIBA-GEIGY CORPORATION (US) | 1982-03-23 | — | — | US | disclosed |
| US-4318791-A | PHOTOPOLYMERIZABLE SYSTEM FOR INKS | CIBA-GEIGY CORPORATION (US) | 1982-03-09 | — | — | US | disclosed |
| US-4315807-A | Sensitizers for photopolymerization | CIBA-GEIGY CORPORATION (US) | 1982-02-16 | — | — | US | disclosed |
| US-4308400-A | AROMATIC HYDROXY KETONES | CIBA-GEIGY A.G. (CH) | 1981-12-29 | — | — | US | disclosed |
| EP-0003002-A2 | Use of aromatic-aliphatic ketones as photoinitiators, photopolymerisable systems containing such ketones and aromatic-aliphatic ketones | CIBA-GEIGY AG (CH) | 1979-07-11 | — | — | EP | disclosed |