SCHEMBL10090157

SCHEMBL10090157

COC(C)(C)C(=O)c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 6/20 0.60
SRC P12931 1/20 0.55
TSHR P16473 3/20 0.50
ALDH1A1 P00352 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
HSD17B10 Q99714 2/20 0.47
CES2 O00748 4/20 0.44
LMNA P02545 2/20 0.43
F2 P00734 1/20 0.43
DAO P14920 1/20 0.42
NAPRT Q6XQN6 1/20 0.42
ELANE P08246 2/20 0.42
MAPT P10636 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
KCNN4 O15554 1/20 0.41
KDM4E B2RXH2 1/20 0.41
ALOX15 P16050 1/20 0.41
MAPK1 P28482 1/20 0.41
POLB P06746 1/20 0.40
PRSS1 P07477 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10948100 0.92 CES1 (0.56) CES1SRCTSHRALDH1A1TDP1
SCHEMBL10944759 0.92 CES1 (0.53) CES1SRCALDH1A1TDP1LMNA
SCHEMBL16994154 0.85 ACHE (0.46) CES1SRCTSHRALDH1A1TDP1
SCHEMBL2033994 0.84 CES1 (0.52) CES1SRCTSHRALDH1A1TDP1
Benzoin SCHEMBL15910700 0.83 CES1 (0.64) CES1SRCTSHRALDH1A1TDP1
SCHEMBL8332006 0.83 CES1 (0.60) CES1SRCTSHRALDH1A1TDP1
SCHEMBL3661644 0.83 CES1 (0.60) CES1SRCTSHRALDH1A1TDP1
SCHEMBL10712634 0.81 TDP1 (0.52) CES1ALDH1A1TDP1CES2LMNA
SCHEMBL50469 0.81 CES1 (0.58) CES1SRCTSHRALDH1A1TDP1
SCHEMBL2150284 0.80 CES1 (0.62) CES1SRCTSHRALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11066602-B2 Reactive mesogen and liquid crystal composition including the same SAMSUNG DISPLAY CO., LTD. (KR) 2021-07-20 US disclosed
US-11053354-B2 Liquid crystal display device SHARP KABUSHIKI KAISHA (JP) 2021-07-06 US disclosed
US-11009750-B2 Liquid crystal display device and method for producing liquid crystal display device SHARP KABUSHIKI KAISHA (JP) 2021-05-18 US disclosed
US-20200050077-A1 OPTICAL SHUTTER FOR CAMERA MODULE AND PRODUCTION METHOD THEREOF SHARP KABUSHIKI KAISHA (JP) 2020-02-13 US disclosed
US-20190276741-A1 REACTIVE MESOGEN AND LIQUID CRYSTAL COMPOSITION INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2019-09-12 US disclosed
US-20190271886-A1 CURVED LIQUID CRYSTAL DISPLAY DEVICE SAMSUNG DISPLAY CO LTD (KR) 2019-09-05 US disclosed
US-20190227387-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD FOR PRODUCING LIQUID CRYSTAL DISPLAY DEVICE SHARP KABUSHIKI KAISHA (JP) 2019-07-25 US disclosed
US-10344213-B2 Reactive mesogen and liquid crystal composition including the same SAMSUNG DISPLAY CO., LTD. (KR) 2019-07-09 US disclosed
US-10338436-B2 Method of manufacturing curved liquid crystal display device and curved liquid crystal display device SAMSUNG DISPLAY CO., LTD. (KR) 2019-07-02 US disclosed
US-9941543-B2 Non-aqueous liquid electrolyte for secondary battery and secondary battery FUJIFILM CORPORATION (JP) 2018-04-10 US disclosed
US-8148541-B2 Rhodanine derivatives, a process for the preparation thereof and pharmaceutical composition containing the same KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2012-04-03 US disclosed
US-20090042872-A1 Rhodanine Derivatives, a Process for the Preparation Thereof and Pharmaceutical Composition Containing the Same KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2009-02-12 US disclosed
US-20080095847-A1 STIMULUS-RELEASE CARRIER, METHODS OF MANUFACTURE AND METHODS OF TREATMENT ADVANCED CARDIOVASCULAR SYSTEMS, INC. 2008-04-24 US disclosed
EP-1728838-B1 Ink composition for ink jet-recording and method for preparing lithographic printing plate using the same FUJIFILM CORP (JP) 2007-08-15 EP disclosed
US-4960746-A A-HYDROXY-OR A-AMINO-ACETOPHENONES AND A TITANOCENE COMPOUND SUBSTITUTED BY FLUORINE CIBA-GEIGY CORPORATION (US) 1990-10-02 US disclosed
US-4321118-A Bis benzoyl sensitizers for photopolymerization or photo cross linking process and composition CIBA-GEIGY CORPORATION (US) 1982-03-23 US disclosed
US-4318791-A PHOTOPOLYMERIZABLE SYSTEM FOR INKS CIBA-GEIGY CORPORATION (US) 1982-03-09 US disclosed
US-4315807-A Sensitizers for photopolymerization CIBA-GEIGY CORPORATION (US) 1982-02-16 US disclosed
US-4308400-A AROMATIC HYDROXY KETONES CIBA-GEIGY A.G. (CH) 1981-12-29 US disclosed
EP-0003002-A2 Use of aromatic-aliphatic ketones as photoinitiators, photopolymerisable systems containing such ketones and aromatic-aliphatic ketones CIBA-GEIGY AG (CH) 1979-07-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11066602-B2 Reactive mesogen and liquid crystal composition including the same SPIN2B, ZYX, ZP1 CES1 4282/4885SRC 349/4885TSHR 4693/4885
US-20080095847-A1 STIMULUS-RELEASE CARRIER, METHODS OF MANUFACTURE AND METHODS OF TREATMENT TNF, RYR2, IL1B CES1 1362/4885SRC 919/4885TSHR 2182/4885
US-20090042872-A1 Rhodanine Derivatives, a Process for the Preparation Thereof and Pharmaceutical Composition Containing the Same PTPRR, PTPRG, PTPRS CES1 1016/4885SRC 365/4885TSHR 144/4885
US-10344213-B2 Reactive mesogen and liquid crystal composition including the same SCO2, CCNL2, CCNB2 CES1 893/4885SRC 1260/4885TSHR 1110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.