Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 12/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11228357 | 0.95 | HTR4 (0.49) | HTR4DRD4DRD3DRD2 | |
| SCHEMBL7296558 | 0.89 | HTR4 (0.60) | HTR4DRD4 | |
| SCHEMBL11243059 | 0.87 | HTR4 (0.51) | HTR4DRD4DRD2 | |
| SCHEMBL11236108 | 0.87 | HTR4 (0.51) | HTR4DRD4DRD2 | |
| SCHEMBL11235740 | 0.86 | HTR4 (0.69) | HTR4DRD2 | |
| SCHEMBL11243730 | 0.84 | DRD2 (0.54) | DRD4DRD3DRD2 | |
| SCHEMBL11243700 | 0.84 | DRD2 (0.63) | DRD4DRD3DRD2 | |
| SCHEMBL11242259 | 0.84 | DRD2 (0.54) | DRD4DRD3DRD2 | |
| SCHEMBL11237343 | 0.84 | DRD2 (0.63) | DRD4DRD3DRD2 | |
| SCHEMBL11235259 | 0.83 | DRD2 (0.53) | DRD4DRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4352802-A | DESALINATION OF SEA WATER | BEECHAM GROUP LIMITED (GB) | 1982-10-05 | — | — | US | disclosed |
| EP-0041817-A1 | Benzamide derivatives, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1981-12-16 | — | — | EP | disclosed |